ROS1 antibody (pTyr2274)

Catalog No. ABIN8120067

The Rabbit Polyclonal anti-ROS1 antibody is suitable to detect ROS1 in samples from Human, Rat and Mouse. It has been validated for WB and IF.

Quick Overview for ROS1 antibody (pTyr2274) (ABIN8120067)

Target: ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ROS1 Antibody

Binding Specificity: pTyr2274

Purpose: ROS1 (Phospho Tyr2274) Antibody

Specificity: This antibody detects endogenous levels of Human ROS1 (phospho-Tyr2274)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human ROS1 (Tyr2274)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ROS1

Target: ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

Alternative Name: ROS1

Background:

Synonyms: Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)

Background: This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes.The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008],

Gene Name: ROS1 MCF3 ROS

Protein Name: ROS1 (Tyr2274)

Gene ID: 6098

UniProt: P08922

Pathways: RTK Signaling