CAMK2B antibody (pThr286)

Catalog No. ABIN8120134

The Rabbit Polyclonal anti-CAMK2B antibody (ABIN8120134) specifically detects CAMK2B in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for CAMK2B antibody (pThr286) (ABIN8120134)

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CAMK2B Antibody

Binding Specificity: pThr286

Purpose: CaMK2 (Phospho Thr286) Antibody

Specificity: This antibody detects endogenous pospho levels of human CaMK2 (Phospho-Thr286)

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA(peptide)1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Alternative Name: CaMK2

Background:

Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta, CaMK-II subunit delta, EC 2.7.11.17)

Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

Gene Name: CAMK2D CAMKD

Protein Name: CaMK2 (Phospho-Thr286)

Gene ID: 817

UniProt: Q9UQM7

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity