Crossover junction endonuclease EME1 (EME1) (AA 250-330) antibody

Catalog No. ABIN8120755

The Rabbit Polyclonal anti-Crossover junction endonuclease EME1 antibody (ABIN8120755) specifically detects Crossover junction endonuclease EME1 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Crossover junction endonuclease EME1 (EME1) (AA 250-330) antibody (ABIN8120755)

Target: Crossover junction endonuclease EME1 (EME1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Binding Specificity: AA 250-330

Purpose: Eme1 Antibody

Specificity: Eme1 Polyclonal Antibody detects endogenous levels of Eme1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Eme1 . at AA range: 250-330

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details

Target: Crossover junction endonuclease EME1 (EME1)

Alternative Name: Eme1

Background:

Synonyms: EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4

Background: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],

Gene Name: EME1

Protein Name: Crossover junction endonuclease EME1

Gene ID: 146956

UniProt: Q96AY2