GLIS3 antibody (AA 381-431)

Catalog No. ABIN8121667

The Rabbit Polyclonal anti-GLIS3 antibody (ABIN8121667) specifically detects GLIS3 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for GLIS3 antibody (AA 381-431) (ABIN8121667)

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLIS3 Antibody

Binding Specificity: AA 381-431

Purpose: GLIS3 Antibody

Specificity: This antibody detects endogenous levels of GLIS3 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GLIS3 AA range: 381-431

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Alternative Name: GLIS3

Background:

Background: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008],

Gene Name: GLIS3 ZNF515

Protein Name: GLIS3

Gene ID: 169792

UniProt: Q8NEA6