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BMI1 antibody

BMI1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal unconjugated
Catalog No. ABIN781173
  • Target See all BMI1 Antibodies
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Reactivity
    • 110
    • 47
    • 26
    • 11
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 77
    • 31
    • 6
    Mouse
    Clonality
    • 78
    • 36
    Monoclonal
    Conjugate
    • 77
    • 8
    • 8
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMI1 antibody is un-conjugated
    Application
    • 91
    • 49
    • 40
    • 20
    • 14
    • 13
    • 11
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    Nucleus
    Purification
    Protein G-Sepharose affinity purified
    Immunogen
    Synthetic peptide from the N-terminal region of human Bmi1, conjugated to KLH.
    Isotype
    IgG
    Top Product
    Discover our top product BMI1 Primary Antibody
  • Application Notes
    Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    50µg/50µl
    Buffer
    0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Alternative Name
    Bmi1 (BMI1 Products)
    Synonyms
    FLVI2/BMI1 antibody, PCGF4 antibody, RNF51 antibody, AW546694 antibody, Bmi-1 antibody, Pcgf4 antibody, bmi1 antibody, pcgf4 antibody, psc1 antibody, wu:fb17g03 antibody, wu:fd18f06 antibody, BMI-1 antibody, pcgf4b antibody, bmi-1 antibody, bmi1-a antibody, bmi1-b antibody, bmi1b antibody, rnf51 antibody, xbmi-1 antibody, BMI1 proto-oncogene, polycomb ring finger antibody, BMI1 polycomb ring finger oncogene antibody, Bmi1 polycomb ring finger oncogene antibody, bmi1 polycomb ring finger oncogene 1a antibody, bmi1 polycomb ring finger oncogene 1b antibody, BMI1 proto-oncogene, polycomb ring finger L homeolog antibody, BMI1 antibody, LOC100230513 antibody, Bmi1 antibody, bmi1a antibody, bmi1b antibody, bmi1.L antibody
    Background
    The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
    Molecular Weight
    37kDa
    NCBI Accession
    NM_005180
    Pathways
    Cell Division Cycle, Autophagy
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