NCOA1 antibody

Catalog No. ABIN781197

The Mouse Monoclonal anti-NCOA1 antibody (ABIN781197) specifically detects NCOA1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for NCOA1 antibody (ABIN781197)

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NCOA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NCOA1 Antibody

Specificity: Nucleus

Purification: Protein G-Sepharose affinity purified.

Immunogen: Recombinant fragment of Human NCOA1 (C-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Alternative Name: NCOA1

Background: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 80kDa

NCBI Accession: NM_003743

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha