MX1 antibody

Catalog No. ABIN781793

Product Details anti-MX1 Antibody

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reactivity: Cow, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity Chromatography

Immunogen: Recombinant Porcine Mx1 protein

Clone: AM39

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore by adding 0.5 mL distilled water.

Concentration: 0.4 mg/mL

Buffer: Stock solution contains PBS, pH 7.2 with 5 mg/mL BSA as a stabilizer and 0.09 % Sodium Azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: Mx1 (MX1 Products)

Synonyms: IFI78 antibody, AI893580 antibody, Mx antibody, Mx-1 antibody, IFI-78K antibody, MX antibody, MxA antibody, Mx1-b antibody, Mx1B antibody, OGTPBP antibody, ONBP antibody, myxovirus (influenza virus) resistance 1 antibody, MX dynamin-like GTPase 1 antibody, MX dynamin like GTPase 1 antibody, Mx1 antibody, MX1 antibody

Background: Mx proteins are cytoplasmic proteins induced by type-1 interferons (α and β) in leukocytes. However, there is a baseline level of expression even in the absence of viral infection. In humans, mainly monocytes and lymphocytes have been shown to express the Mx gene, whereas Mx expression is low in granulocytes. Mx proteins are high molecular weight GTPases of 70 - 80kD which belong to the dynamin superfamily. Mx proteins have a strong propensity to aggregate and form homooligomers. A unique property is their antiviral activity against many RNA viruses.Synonyms: Mx1 protein