IL17D antibody (Biotin)

Catalog No. ABIN783047

Product Details anti-IL17D Antibody (Biotin)

Target: IL17D (Interleukin 17D (IL17D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17D antibody is conjugated to Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Recognizes Interleukin-17D / IL17D

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography employing an immobilized Human 17D matrix

Immunogen: Highly pure recombinant Human IL-17D.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Centrifuge vial prior to opening. Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

Expiry Date: 6 months

Target Details for IL17D

Target: IL17D (Interleukin 17D (IL17D))

Alternative Name: Interleukin-17D / IL17D (IL17D Products)

Synonyms: IL-17D antibody, IL-22 antibody, IL-27 antibody, IL27 antibody, AI462269 antibody, Il27a antibody, il17-4 antibody, zgc:194257 antibody, zgc:194303 antibody, IL-27p28 antibody, Il30 antibody, p28 antibody, interleukin 17D antibody, interleukin 17d antibody, interleukin 27 antibody, IL17D antibody, Il17d antibody, il17d antibody, Il27 antibody

Background: The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 155 amino acid chains, secreted by activated T-cells and acts on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region and differ from one another in their N-terminal segments and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as disulfide-linked homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays.Synonyms: IL-17D, IL27, Interleukin-27

Gene ID: 53342

NCBI Accession: NP_612141

UniProt: Q8TAD2

Pathways: Cellular Response to Molecule of Bacterial Origin