ZMYM1 antibody (C-Term)

Catalog No. ABIN783365

Product Details anti-ZMYM1 Antibody

Target: ZMYM1 (Zinc Finger, MYM-Type 1 (ZMYM1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYM1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ZMYM1 at C-term. At least two isoforms of ZMYM1 are known to exist, this antibody will detect only the shorter isoform. ZMYM1 antibody is predicted to not cross-react with other ZMYM protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human ZMYM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for ZMYM1

Target: ZMYM1 (Zinc Finger, MYM-Type 1 (ZMYM1))

Alternative Name: ZMYM1 (ZMYM1 Products)

Synonyms: 5830412B09Rik antibody, AW209050 antibody, MYM antibody, RP11-181E22.4 antibody, zinc finger, MYM domain containing 1 antibody, zinc finger MYM-type containing 1 antibody, Zmym1 antibody, ZMYM1 antibody

Background: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.Synonyms: Zinc finger MYM-type protein 1

Gene ID: 79830

NCBI Accession: NP_079048

UniProt: Q5SVZ6