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TYW3 antibody (Center)

TYW3 Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783490
  • Target See all TYW3 Antibodies
    TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))
    Binding Specificity
    • 2
    • 1
    Center
    Reactivity
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 3
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    This TYW3 antibody is un-conjugated
    Application
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TYW3 at Center. TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist, this antibody will detect both isoforms.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide near the center of human TYW3
    Top Product
    Discover our top product TYW3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))
    Alternative Name
    TYW3 (TYW3 Products)
    Synonyms
    C1orf171 antibody, 5230400J09Rik antibody, tRNA-yW synthesizing protein 3 homolog L homeolog antibody, tRNA-yW synthesizing protein 3 homolog antibody, tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) antibody, tyw3.L antibody, TYW3 antibody, Tyw3 antibody
    Background
    TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.Synonyms: C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3
    Gene ID
    127253
    NCBI Accession
    NP_612476
    UniProt
    Q6IPR3
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