RGS17 antibody (AA 148-160)

Catalog No. ABIN784001

The Rabbit Polyclonal anti-RGS17 antibody has been validated for WB and IF. It is suitable to detect RGS17 in samples from Human.

Quick Overview for RGS17 antibody (AA 148-160) (ABIN784001)

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS17 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RGS17 Antibody

Binding Specificity: AA 148-160

Specificity: Recognizes RGS17.
Cellular Localization: Membrane, Lipid-anchor, Nucleus, Cytoplasm.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 148 and 160 of Human RGS17.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 1xPBS, 1 % BSA, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for RGS17

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Alternative Name: RGS17

Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Synonyms: RGS-17, RGSZ2, Regulator of G-protein signaling 17

Gene ID: 26575, 9606

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling