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RGS17 antibody (Regulator of G-Protein Signaling 17) (C-Term) Primary Antibody

RGS17 Reactivity: Human ICC, IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856380
$509.08
Plus shipping costs $45.00
100 μL
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  • Target
    RGS17
    Binding Specificity
    C-Term
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human
    • 22
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Host
    Rabbit
    • 11
    • 7
    • 2
    • 2
    Clonality
    Polyclonal
    Conjugate
    This RGS17 antibody is un-conjugated
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
    • 15
    • 12
    • 3
    • 1
    • 1
    • 1
    Characteristics
    Rabbit Polyclonal antibody to RGS17 (regulator of G-protein signaling 17)
    RGS17 antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RGS17. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:1000-1:10000*
    Comment

    Positive Control: 293T transfected recombinant RGS17

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    RGS17
    Alternative Name
    RGS17 (RGS17 Antibody Abstract)
    Synonyms
    RGS17, zgc:92802, MGC179306, RGS-17, RGSZ2, hRGS17, 6430507P11Rik, Rgsz2, regulator of G protein signaling 17, regulator of G-protein signaling 17, RGS17, Rgs17, rgs17
    Background
    This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

    Cellular Localization: Membrane, Lipid-anchor , Nucleus , Cytoplasm
    Molecular Weight
    24 kDa
    Gene ID
    26575
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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