CTCF antibody
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- Target See all CTCF Antibodies
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
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Reactivity
- Human, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CTCF antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human CTCF expressed in E. Coli.
- Clone
- 1D11
- Isotype
- IgG1
- Top Product
- Discover our top product CTCF Primary Antibody
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- Application Notes
- WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100g/100l
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
- Alternative Name
- CTCF (CTCF Products)
- Synonyms
- im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
- Background
- This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Tissue specificity: Ubiquitous. Absent in primary spermatocytes. Synonyms: CTCF
- Molecular Weight
- 83kDa
- Gene ID
- 10664
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