×
For best experience we recommend to activate Javascript in your browser.
PERK antibody
EIF2AK3
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
5G5
unconjugated
Product Details anti-PERK Antibody
(hide)
Target
See all PERK (EIF2AK3) Antibodies
PERK (EIF2AK3)
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
Reactivity
All reactivities for PERK antibodies
Human
Host
All hosts for PERK antibodies
Mouse
Clonality
All clonalities for PERK antibodies
Monoclonal
Conjugate
All conjugates for PERK antibodies
This PERK antibody is un-conjugated
Application
All applications for PERK antibodies
Western Blotting (WB), ELISA
Purification
Ascitic fluid
Immunogen
Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.
Clone
5G5
Isotype
IgG1
Top Product
Discover our top product EIF2AK3 Primary Antibody
Alternatives
(show)
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (pThr980) antibody
EIF2AK3
Reactivity: Human, Mouse, Rat, Dog, Pig
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
(hide)
Application Notes
WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
100g/100l
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target Details for PERK
(hide)
Target
PERK (EIF2AK3)
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
Alternative Name
EIF2AK3 (EIF2AK3 Products )
Synonyms
EIF2AK3 antibody, AI427929 antibody, Pek antibody, Perk antibody, PEK antibody, PERK antibody, WRS antibody, eukaryotic translation initiation factor 2 alpha kinase 3 antibody, EIF2AK3 antibody, Eif2ak3 antibody
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. Synonyms: PAX8
Molecular Weight
125kDa
Gene ID
9451
Pathways
Hormone Transport , ER-Nucleus Signaling , Positive Regulation of Endopeptidase Activity , Hepatitis C , Unfolded Protein Response
Recently viewed
(hide)