TFE3 antibody (AA 303-307)
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- Target See all TFE3 Antibodies
- TFE3 (Transcription Factor E3 (TFE3))
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Binding Specificity
- AA 303-307
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TFE3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- The antibody detects endogenous levels of total TFE3 protein.
- Purification
- Affinity purified
- Immunogen
- Peptide sequence around AA 303-307 (L-D-V-Y-S) derived from Human TFE3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product TFE3 Primary Antibody
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- Application Notes
- Western blotting: 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- TFE3 (Transcription Factor E3 (TFE3))
- Alternative Name
- TFE3 (TFE3 Products)
- Synonyms
- RCCP2 antibody, RCCX1 antibody, TFEA antibody, bHLHe33 antibody, F830016E06Rik antibody, Tcfe3 antibody, Tfe-3 antibody, RGD1559642 antibody, cb873 antibody, zgc:109815 antibody, transcription factor binding to IGHM enhancer 3 antibody, transcription factor E3 antibody, transcription factor binding to IGHM enhancer 3 S homeolog antibody, transcription factor binding to IGHM enhancer 3a antibody, TFE3 antibody, Tfe3 antibody, tfe3.S antibody, tfe3a antibody
- Background
- Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
- Molecular Weight
- 70 kDa
- Gene ID
- 7030
- NCBI Accession
- NP_006512
- UniProt
- P19532
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