MAP2K3 antibody (pThr222) (AbBy Fluor® 488)

Catalog No. ABIN877751

The Rabbit Polyclonal anti-MAP2K3 antibody is suitable to detect MAP2K3 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for MAP2K3 antibody (pThr222) (AbBy Fluor® 488) (ABIN877751)

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K3 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MAP2K3 Antibody (AbBy Fluor® 488)

Binding Specificity: pThr222

Purpose: phospho-MEK3 (Thr222) Polyclonal Antibody, AbBy Fluor-488 Conjugated

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MEK3 around the phosphorylation site of Thr222

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAP2K3

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Alternative Name: MEK3

Background:

Synonyms: Dual specicity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, map2k3, MAPK ERK kinase 3, MAPK/ERK kinase 3, MAPKK 3, MAPKK3, MEK 3, MEK3, Mitogen activated protein kinase kinase 3, MKK3, MP2K3_HUMAN, PRKMK3.

Background: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.

Gene ID: 5606

Pathways: MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2