Phospholipase C gamma 2 antibody (pTyr759) (Alexa Fluor 488)
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- Target See all Phospholipase C gamma 2 (PLCG2) Antibodies
- Phospholipase C gamma 2 (PLCG2)
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Binding Specificity
- pTyr759
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Phospholipase C gamma 2 antibody is conjugated to Alexa Fluor 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr759
- Isotype
- IgG
- Top Product
- Discover our top product PLCG2 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Phospholipase C gamma 2 (PLCG2)
- Alternative Name
- PLC gamma 2 (PLCG2 Products)
- Synonyms
- PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
- Background
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Synonyms: PLC 2, PLC gamma 2, PLC IV, PLCG2, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2, EC 3.1.4.11, Phosphoinositide phospholipase C, Phospholipase C gamma 2, Phospholipase C, gamma 2 phosphatidylinositol specic, PLCG2_HUMAN.
Background: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011].
- Gene ID
- 5336
- Pathways
- RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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