HTR3C antibody (AA 101-200) (Alexa Fluor 555)

Catalog No. ABIN880576

Product Details anti-HTR3C Antibody (Alexa Fluor 555)

Target: HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR3C antibody is conjugated to Alexa Fluor 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT3C

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HTR3C

Target: HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))

Alternative Name: 5HT3C (HTR3C Products)

Synonyms: 5-hydroxytryptamine receptor 3C antibody, 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic antibody, HTR3C antibody, LOC100066962 antibody, LOC607416 antibody, LOC706232 antibody

Background:

Synonyms: 5-HT-3, 5-HT3 receptor subunit E splice variant HTR3Ea, 5-HT3c1, 5-HT3E, 5-HT3R, 5-hydroxytryptamine serotonin receptor 3, family member E, 5-hydroxytryptamine receptor 3 subunit E, 5-hydroxytryptamine receptor 3E, 5HT3c1, 5HT3E, 5HT3R, HTR3, SEROTONIN 5-HT-3E RECEPTOR, serotonin receptor 3 subunit E, Serotonin receptor 3E.

Background: HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.

Gene ID: 285242