BPI antibody (AA 141-240) (Alexa Fluor 555)

Catalog No. ABIN885433

Product Details anti-BPI Antibody (Alexa Fluor 555)

Target: BPI (Bactericidal/Permeability Increasing Protein (BPI))

Binding Specificity: AA 141-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPI antibody is conjugated to Alexa Fluor 555

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BPI

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BPI

Target: BPI (Bactericidal/Permeability Increasing Protein (BPI))

Alternative Name: BPI (BPI Products)

Synonyms: 9230105K17Rik antibody, Bpifd1 antibody, BPIFD1 antibody, rBPI antibody, bpi antibody, bpi.L antibody, lbp antibody, bactericidal/permeability-increasing protein antibody, bactericidal permeablility increasing protein antibody, bactericidal/permeability-increasing protein S homeolog antibody, BPI antibody, Bpi antibody, bpi.S antibody

Background:

Synonyms: Bactericidal permeability-increasing protein, bactericidal/permeability-increasing protein, BPI, CAP 57, BPI_HUMAN.

Background: The antimicrobial protein Bactericidal Permeability Increasing protein (BPI) is a 55 kDa protein found in the primary granules of polymorhonuclear leukocytes (PMN). The cytotoxicity action of BPI is limited to gram negative bacteria, reflecting the high affinity of BPI for bacterial LPS. Binding of BPI to live bacteria via LPS causes anti-infective activites: 1) cytotoxicity via sequential damage to bacterial outer and inner lipid membranes, 2) neutralization of gram-negative bacterial LPS, 3) opsonization of bacteria to enhance phagocytosis by neutrophils.

Gene ID: 671