ZMYND11 antibody (AA 501-602) (HRP)

Catalog No. ABIN885595

Product Details anti-ZMYND11 Antibody (HRP)

Target: ZMYND11 (Zinc Finger, MYND-Type Containing 11 (ZMYND11))

Binding Specificity: AA 501-602

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYND11 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adenovirus 5 E1A binding protein

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZMYND11

Target: ZMYND11 (Zinc Finger, MYND-Type Containing 11 (ZMYND11))

Alternative Name: Adenovirus 5 E1A binding protein (ZMYND11 Products)

Synonyms: BRAM1 antibody, BS69 antibody, wu:fi38d06 antibody, zgc:110370 antibody, zgc:152745 antibody, bs69 antibody, bram1 antibody, 2210402G22Rik antibody, ZMYND11 antibody, DKFZp459I035 antibody, zinc finger MYND-type containing 11 antibody, zinc finger, MYND-type containing 11 antibody, zinc finger, MYND domain containing 11 antibody, Zinc finger MYND domain-containing protein 11 antibody, ZMYND11 antibody, zmynd11 antibody, Zmynd11 antibody, zmy11 antibody

Background:

Synonyms: BS69, BRAM1, MRD30, Zinc finger MYND domain-containing protein 11, Adenovirus 5 E1A-binding protein, Bone morphogenetic protein receptor-associated molecule 1, Protein BS69, ZMYND11

Background: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Gene ID: 10771

UniProt: Q15326