CCDC36 antibody (AA 131-230) (HRP)

Catalog No. ABIN887650

Product Details anti-CCDC36 Antibody (HRP)

Target: CCDC36 (Coiled-Coil Domain Containing 36 (CCDC36))

Binding Specificity: AA 131-230

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC36 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC36/CT74

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC36

Target: CCDC36 (Coiled-Coil Domain Containing 36 (CCDC36))

Alternative Name: CT74 (CCDC36 Products)

Synonyms: CT74 antibody, coiled-coil domain containing 36 antibody, CCDC36 antibody, Ccdc36 antibody

Background:

Synonyms: Cancer/testis antigen 74, CCD36_HUMAN, Ccdc36, Coiled-coil domain-containing protein 36, CT74, FLJ25320.

Background: CCDC36 , also known as CT74 (cancer/testis antigen 74), is a 584 amino acid protein that contains coiled-coil domains and is expressed as three alternatively spliced isoforms. The gene encoding CCDC36 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Gene ID: 339834