MFSD2A antibody (Major Facilitator Superfamily Domain Containing 2A) (AA 345-395) (Alexa Fluor 555)

Details for Product anti-MFSD2A Antibody No. ABIN906278, Supplier: Log in to see
Antigen
  • 1700018O18Rik
  • Mfsd2
  • RGD1310174
  • MFSD2
  • NLS1-A
  • Sodium-dependent LPC symporter 1-A
  • mfsd2a
  • zgc:101615
  • mfsd2
  • NLS1-B
  • Sodium-dependent LPC symporter 1-B
  • mfsd2b
  • zgc:101069
  • major facilitator superfamily domain containing 2A
  • major facilitator superfamily domain containing 2aa
  • major facilitator superfamily domain containing 2A L homeolog
  • major facilitator superfamily domain containing 2ab
  • MFSD2A
  • mfsd2a
  • Mfsd2a
  • mfsd2aa
  • mfsd2a.L
  • mfsd2ab
Epitope
AA 345-395
14
10
2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
34
26
24
2
1
1
1
1
1
1
Host
Rabbit
34
Clonality
Polyclonal
Conjugate
This MFSD2A antibody is conjugated to Alexa Fluor 555
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
22
15
14
12
8
4
2
1
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Immunogen KLH conjugated synthetic peptide derived from human MFSD2A
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others MFSD2A products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Mfsd2a (MFSD2A Antibody Abstract)
Background

Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).

Subcellular location: Intracellular

Synonyms: NLS1, MFSD2, Sodium-dependent lysophosphatidylcholine symporter 1, Sodium-dependent LPC symporter 1, Major facilitator superfamily domain-containing protein 2A, MFSD2A, HMFN0656, PP9177, UNQ300/PRO341

Gene ID 84879
UniProt Q8NA29
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months
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