CBX5 antibody (pTyr37) (Alexa Fluor 488)

Catalog No. ABIN911052

Product Details anti-CBX5 Antibody (Alexa Fluor 488)

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Binding Specificity: pTyr37

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX5 antibody is conjugated to Alexa Fluor 488

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CBX5 around the phosphorylation site of Tyr37

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Alternative Name: CBX5 (CBX5 Products)

Synonyms: HP1 antibody, HP1A antibody, id:ibd2026 antibody, wu:fc63e02 antibody, wu:fe47g12 antibody, wu:fi03h05 antibody, zgc:158601 antibody, CBX5 antibody, cbx5 antibody, MGC64354 antibody, 2610029O15Rik antibody, C75991 antibody, Hp1a antibody, Hp1alpha antibody, chromobox 5 antibody, chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, chromobox 5 S homeolog antibody, CBX5 antibody, cbx5 antibody, Cbx5 antibody, cbx5.S antibody

Background:

Synonyms: Antigen p25, Cbx 5, Cbx5, CBX5_HUMAN, CG8409, Chromobox homolog 5 Drosophila HP1 alpha, Chromobox homolog 5 HP1 alpha homolog Drosophila, Chromobox homolog 5 HP1 alpha homolog, Drosophila, chromobox homolog 5, HP1 alpha homolog, Chromobox protein homolog 5, Chromobox protein homologue 5, Heterochromatin protein 1 alpha, Heterochromatin protein 1, Heterochromatin protein 1, HP 1, HP 1A, HP1 alpha homolog, HP1, HP1A, HP1Hs alpha, Suvar205, HP1a, HP1Hs-alpha, HP1 alpha, Antigen p25, Heterochromatin protein 1 homolog alpha.

Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].

Gene ID: 23468