TRERF1 antibody (AA 101-200) (HRP)

Catalog No. ABIN918564

Product Details anti-TRERF1 Antibody (HRP)

Target: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRERF1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TReP132/RAPA

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRERF1

Target: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Alternative Name: TReP132 (TRERF1 Products)

Synonyms: BCAR2 antibody, HSA277276 antibody, RAPA antibody, RP1-139D8.5 antibody, TREP132 antibody, TReP-132 antibody, dJ139D8.5 antibody, 9430096I18Rik antibody, AI429294 antibody, B830015H24 antibody, Trep-132 antibody, Trep132 antibody, transcriptional regulating factor 1 antibody, TRERF1 antibody, Trerf1 antibody

Background:

Synonyms: BCAR2, Breast cancer anti estrogen resistance 2, Breast cancer anti-estrogen resistance 2, RAPA, rapa 1, rapa 2, rapa1, rapa2, RP1 139D8.5, Transcriptional regulating factor 1, Transcriptional regulating protein 132, Transcriptional-regulating factor 1, Transcriptional-regulating protein 132, TREF1_HUMAN, TReP 132, TREP132, TRERF1, Zinc finger protein rapa, Zinc finger transcription factor TReP 132, Zinc finger transcription factor TReP-132.

Background: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.

Gene ID: 55809

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding