VCAM1 antibody (AA 651-739) (Alexa Fluor 488)

Catalog No. ABIN919518

Product Details anti-VCAM1 Antibody (Alexa Fluor 488)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Binding Specificity: AA 651-739

Reactivity: Human, Mouse, Rat, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VCAM1 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rabbit, Rat, Sheep

Predicted Reactivity: Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VCAM-1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Alternative Name: VCAM1 (VCAM1 Products)

Synonyms: CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody

Background:

Synonyms: CD106, INCAM-1, Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, VCAM1, L1CAM

Background: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

Gene ID: 7412

UniProt: P19320

Pathways: Carbohydrate Homeostasis