PROC
Reactivity: Human
ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
Supplied in liquid form in a buffered stabilizer solution containing 50 % (v/v) glycerol.
Handling Advice
Avoid repeated freeze/thaw cycles. Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. Dilute only prior to immediate use.
Storage
-20 °C
Storage Comment
Store at -10 to -20 °C.
Huckriede, Beurskens, Wildhagen, Reutelingsperger, Wichapong, Nicolaes: "Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3." in: Journal of thrombosis and haemostasis : JTH, Vol. 21, Issue 12, pp. 3557-3567, (2023) (PubMed).
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Target Type
Viral Protein
Background
Protein C is a zymogenic protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. Activated protein C (APC) performs these operations primarily by proteolytically inactivating proteins Factor Va and Factor VIIIa. Synonyms: Polyclonal Protein C antibody, Anti-Protein C antibody.