HIST1H2AE antibody (Middle Region)

Catalog No. ABIN926642

Product Details anti-HIST1H2AE Antibody

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2AE antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: HIST1 H1 E antibody was raised in rabbit using the middle region of HIST1 1 E as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

HIST1H2AE Blocking Peptide, catalog no. 33R-10412, is also available for use as a blocking control in assays to test for specificity of this HIST1H2AE antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HIST1H2AE

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Alternative Name: HIST1H2AE (HIST1H2AE Products)

Synonyms: H2A.1 antibody, H2A.2 antibody, H2A/a antibody, H2AFA antibody, histone cluster 1 H2A family member e antibody, HIST1H2AE antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. Synonyms: Polyclonal HIST1H2AE antibody, Anti-HIST1H2AE antibody, histone cluster 1, H2ae antibody, H2A.1 antibody, H2A.2 antibody, H2A/a antibody, H2AFA antibody, HIST1H2AB antibody.

Pathways: Telomere Maintenance