CDC42 antibody (N-Term)
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- Target See all CDC42 Antibodies
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Chicken
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDC42 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus), Chicken, Dog (Canine)
- Purification
- Purified
- Immunogen
- CDC42 antibody was raised in rabbit using the N terminal of CDC42 as the immunogen
- Top Product
- Discover our top product CDC42 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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CDC42 Blocking Peptide, catalog no. 33R-2092, is also available for use as a blocking control in assays to test for specificity of this CDC42 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- Alternative Name
- CDC42 (CDC42 Products)
- Synonyms
- CDC42Hs antibody, G25K antibody, AI747189 antibody, AU018915 antibody, cdc42a antibody, wu:fb07d08 antibody, wu:fj62g06 antibody, zgc:63918 antibody, Xcdc42 antibody, cdc42hs antibody, g25k antibody, CDC42 antibody, CG12530 antibody, Cdc42Dm antibody, D-CDC42 antibody, D-Cdc42 antibody, D-cdc42 antibody, DCDC42 antibody, DCdc42 antibody, Dcdc42 antibody, Dm Cdc42 antibody, DmCDC42 antibody, Dmcdc42 antibody, Dmel\\CG12530 antibody, cdc42 antibody, cell division cycle 42 antibody, Cell division control protein 42 homolog antibody, cell division control protein 42 homolog antibody, cell division cycle 42 L homeolog antibody, CG12530 gene product from transcript CG12530-RC antibody, Rho family GTPase antibody, CDC42 antibody, Cdc42 antibody, cdc42 antibody, LOC100636735 antibody, LOC100637699 antibody, LOC100638834 antibody, cdc42.L antibody
- Background
- CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Synonyms: Polyclonal CDC42 antibody, Anti-CDC42 antibody, cell division cycle 42, GTP binding protein, 25kDa antibody, CDC42Hs antibody, G25K antibody.
- Pathways
- MAPK Signaling, Microtubule Dynamics, RTK Signaling, WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
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