RIPK1 antibody (Middle Region)

Catalog No. ABIN926877

This anti-RIPK1 antibody is a Rabbit Polyclonal antibody detecting RIPK1 in WB. Suitable for Human and Cow.

Quick Overview for RIPK1 antibody (Middle Region) (ABIN926877)

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIPK1 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Cow (Bovine)

Purification: Purified

Immunogen: RIPK1 antibody was raised in rabbit using the middle region of RIPK1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RIPK1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this RIPK1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RIPK1

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Alternative Name: RIPK1

Background: FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex. Synonyms: Polyclonal RIPK1 antibody, Anti-RIPK1 antibody, receptor, TNFRSF-interacting serine-threonine kinase 1 antibody.

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway