LDOC1 antibody (N-Term)

Catalog No. ABIN927753

Product Details anti-LDOC1 Antibody

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Binding Specificity: N-Term

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDOC1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Cow (Bovine)

Purification: Purified

Immunogen: LDOC1 antibody was raised in rabbit using the N terminal of LDOC1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

LDOC1 Blocking Peptide, catalog no. 33R-6579, is also available for use as a blocking control in assays to test for specificity of this LDOC1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for LDOC1

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Alternative Name: LDOC1 (LDOC1 Products)

Synonyms: BCUR1 antibody, Mar7 antibody, Mart7 antibody, RGD1565644 antibody, Gm366 antibody, LDOC1 antibody, LDOC1, regulator of NFKB signaling antibody, regulator of NFKB signaling antibody, LDOC1 antibody, Ldoc1 antibody

Background: LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. Synonyms: Polyclonal LDOC1 antibody, Anti-LDOC1 antibody, leucine zipper, down-regulated in cancer 1 antibody, BCUR1 antibody, Mar7 antibody, Mart7 antibody.