CYP2R1 antibody (Middle Region)

Catalog No. ABIN928290

Product Details anti-CYP2R1 Antibody

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2R1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CYP2 R1 antibody was raised in rabbit using the middle region of CYP2 1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CYP2R1 Blocking Peptide, catalog no. 33R-2952, is also available for use as a blocking control in assays to test for specificity of this CYP2R1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CYP2R1

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Alternative Name: CYP2R1 (CYP2R1 Products)

Synonyms: cytochrome P450 family 2 subfamily R member 1 antibody, cytochrome P450, family 2, subfamily R, polypeptide 1 antibody, cytochrome P450, family 2, subfamily r, polypeptide 1 antibody, CYP2R1 antibody, cyp2r1 antibody, Cyp2r1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. Synonyms: Polyclonal CYP2R1 antibody, Anti-CYP2R1 antibody, cytochrome P450, family 2, subfamily R, polypeptide 1 antibody, MGC4663 antibody.

Pathways: Metabolism of Steroid Hormones and Vitamin D