BSCL2 antibody (C-Term)

Catalog No. ABIN928313

The Rabbit Polyclonal anti-BSCL2 antibody has been validated for WB. It is suitable to detect BSCL2 in samples from Human.

Quick Overview for BSCL2 antibody (C-Term) (ABIN928313)

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSCL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BSCL2 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: BSCL2 antibody was raised in rabbit using the C terminal of BSCL2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BSCL2 Blocking Peptide, (ABIN5612369), is also available for use as a blocking control in assays to test for specificity of this BSCL2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Alternative Name: BSCL2

Background: This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal BSCL2 antibody, Anti-BSCL2 antibody, Berardinelli-Seip congenital lipodystrophy 2, seipin antibody, GNG3LG antibody, HMN5 antibody, MGC4694 antibody, SPG17 antibody.