URI1 antibody (Middle Region)

Catalog No. ABIN928444

Product Details anti-URI1 Antibody

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This URI1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus), Mouse (Murine), Cow (Bovine), Frog

Purification: Purified

Immunogen: C19 orf2 antibody was raised in rabbit using the middle region of C19 RF2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

C19orf2 Blocking Peptide, catalog no. 33R-6699, is also available for use as a blocking control in assays to test for specificity of this C19orf2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Alternative Name: C19orf2 (URI1 Products)

Synonyms: c19orf2 antibody, C19orf2 antibody, NNX3 antibody, PPP1R19 antibody, RMP antibody, URI antibody, URI1 prefoldin-like chaperone L homeolog antibody, URI1, prefoldin like chaperone antibody, uri1.L antibody, URI1 antibody

Background: The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Synonyms: Polyclonal C19orf2 antibody, Anti-C19orf2 antibodyFLJ10575 antibody, NNX3 antibody, RMP antibody, URI antibody.