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MBNL2 antibody (Middle Region)

MBNL2 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN928546
  • Target See all MBNL2 Antibodies
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Binding Specificity
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 24
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken
    Host
    • 23
    • 1
    Rabbit
    Clonality
    • 23
    • 1
    Polyclonal
    Conjugate
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    This MBNL2 antibody is un-conjugated
    Application
    • 21
    • 14
    • 14
    • 13
    • 4
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken, Cow (Bovine), Zebrafish (Brachydanio rerio)
    Purification
    Purified
    Immunogen
    MBNL2 antibody was raised in rabbit using the middle region of MBNL2 as the immunogen
    Top Product
    Discover our top product MBNL2 Primary Antibody
  • Application Notes
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    MBNL2 Blocking Peptide, catalog no. 33R-2607, is also available for use as a blocking control in assays to test for specificity of this MBNL2 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Alternative Name
    MBNL2 (MBNL2 Products)
    Synonyms
    1110002M11Rik antibody, AI047808 antibody, AI837313 antibody, AI849185 antibody, AL118326 antibody, MBLL antibody, R75232 antibody, mKIAA4072 antibody, wu:fj89c04 antibody, MBLL39 antibody, PRO2032 antibody, muscleblind like splicing factor 2 antibody, muscleblind-like splicing regulator 2 antibody, muscleblind like splicing regulator 2 antibody, Mbnl2 antibody, mbnl2 antibody, MBNL2 antibody
    Background
    MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM). Synonyms: Polyclonal MBNL2 antibody, Anti-MBNL2 antibody, muscleblind-like 2, Drosophila antibody, DKFZp781H1296 antibody, MBLL antibody, MBLL39 antibody, MGC120625 antibody, MGC120626 antibody, MGC120628 antibody, PRO2032 antibody.
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