Protein Tob1 (TOB1) (Middle Region) antibody

Catalog No. ABIN928601

Product Details

Target: Protein Tob1 (TOB1)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: TOB1 antibody was raised in rabbit using the middle region of TOB1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TOB1 Blocking Peptide, catalog no. 33R-2054, is also available for use as a blocking control in assays to test for specificity of this TOB1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details

Target: Protein Tob1 (TOB1)

Alternative Name: TOB1 (TOB1 Products)

Synonyms: Tob antibody, Trob antibody, APRO5 antibody, APRO6 antibody, PIG49 antibody, TOB antibody, TROB antibody, TROB1 antibody, tob1 antibody, tob1l antibody, wu:fb54d02 antibody, wu:fb98h12 antibody, wu:fd15f10 antibody, zgc:65837 antibody, transducer of ErbB-2.1 antibody, transducer of ERBB2, 1 antibody, transducer of ERBB2, 1a antibody, transducer of ERBB2, 1 S homeolog antibody, transducer of ERBB2, 1b antibody, Tob1 antibody, TOB1 antibody, tob1a antibody, tob1.S antibody, tob1b antibody

Background: This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. Synonyms: Polyclonal TOB1 antibody, Anti-TOB1 antibody, transducer of ERBB2, 1 antibody, APRO6 antibody, MGC104792 antibody, MGC34446 antibody, PIG49 antibody, TOB antibody, TROB antibody, TROB1 antibody.