Melanophilin antibody (C-Term)

Catalog No. ABIN929254

Product Details anti-Melanophilin Antibody

Target: Melanophilin (MLPH)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melanophilin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: MLPH antibody was raised in rabbit using the C terminal of MLPH as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MLPH Blocking Peptide, catalog no. 33R-6767, is also available for use as a blocking control in assays to test for specificity of this MLPH antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Melanophilin

Target: Melanophilin (MLPH)

Alternative Name: MLPH (MLPH Products)

Synonyms: MGC155106 antibody, LOC100222096 antibody, 2210418F23Rik antibody, 5031433I09Rik antibody, AW228792 antibody, D1Wsu84e antibody, Slac-2a antibody, l(1)-3Rk antibody, l1Rk3 antibody, ln antibody, SLAC2-A antibody, melanophilin antibody, MLPH antibody, mlph antibody, Mlph antibody

Background: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. Synonyms: Polyclonal MLPH antibody, Anti-MLPH antibody, melanophilin antibody, MGC2771 antibody, MGC59733 antibody, SLAC2-A antibody.