Angiotensin I Converting Enzyme 1 antibody

Catalog No. ABIN930813

The Mouse Monoclonal anti-Angiotensin I Converting Enzyme 1 antibody (Clone 9B9) (ABIN930813) specifically detects Angiotensin I Converting Enzyme 1 in WB, ELISA, IP, ICC and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Angiotensin I Converting Enzyme 1 antibody (ABIN930813)

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Angiotensin I Converting Enzyme 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 9B9

Product Details anti-Angiotensin I Converting Enzyme 1 Antibody

Cross-Reactivity: Cat (Feline), Hamster, Monkey, Rat (Rattus)

Immunogen: ACE antibody was raised in mouse using ACE from human lung as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:1,000, ICC: 1:100, IHC-F: 1:1,000, IP: 1:1,000-1:10,000, WB: 1:100
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PBS, pH 7.4, with 150 mM NaCl and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Alternative Name: ACE

Background: Angiotensin I-converting enzyme an exopeptidase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), which mediates extracellular volume (i.e. that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II. Synonyms: Monoclonal ACE antibody, Anti-ACE antibody, CD143 antibody, Angiotensin Converting Enzyme antibody.

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration