Rev antibody
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- Target
- Rev
- Reactivity
- Human Immunodeficiency Virus (HIV)
- Host
- Mouse
- Clonality
- Monoclonal
- Application
- ELISA, Western Blotting (WB)
- Purity
- > 95 % pure
- Immunogen
- HIV1 rev antibody was raised in mouse using full length recombinant rev (HIV-1) produced in E.coli expression system as the immunogen.
- Clone
- RMAb6
- Isotype
- IgG1
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- Application Notes
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ELISA: 1:1,000, WB: 1:500
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in sterile distilled water.
- Concentration
- Lot specific
- Buffer
- Supplied lyophilized from PBS buffer, with no preservatives added
- Preservative
- Without preservative
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -70 °C for long term storage.
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- Target
- Rev
- Target Type
- Viral Protein
- Background
- Rev is a HIV gene. The gene's protein product allows fragments of HIV mRNA that contain a Rev Response Element (RRE) to be exported from the nucleus to the cytoplasm. In the absence of the rev gene, the host RNA splicing machinery in the nucleus quickly splices the RNA so that only the smaller, regulatory proteins can be produced, in the presence of rev, RNA is exported from the nucleus before it can be spliced, so that the structural proteins and RNA genome can be produced. Synonyms: Monoclonal HIV1 Rev antibody, Anti-HIV1 Rev antibody, Anti-repression transactivator protein antibody, art/trs antibody, HIV1gp6 antibody, Human immunodeficiency virus 1 Rev antibody, Protein Rev antibody, Regulator of expression of viral proteins antibody, Rev antibody.
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