CDK4 antibody

Catalog No. ABIN933549

This anti-CDK4 antibody is a Mouse Monoclonal antibody detecting CDK4 in WB and IHC. Suitable for Human.

Quick Overview for CDK4 antibody (ABIN933549)

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: DCS-156

Product Details anti-CDK4 Antibody

Purification: Protein A affinity chromatography

Immunogen: Cyclin Dependent Kinase 4 antibody was raised in mouse using human recombinant full-length cdk4 polypeptide as the immunogen.

Isotype: IgG1

Application Details

Application Notes: IHC: 1:10
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in distilled water, final solution contains 0.09 % sodium azide, 0.5 % BSA in PBS buffer, pH 7.4

Concentration: Lot specific

Buffer: Supplied in lyophilized form.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for CDK4

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Alternative Name: CDK4

Background: Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. In fact, yeast cells can proliferate normally when their CDK gene has been replaced with the homologous human gene. CDK4 deficiency has been linked to insulin deficient diabetes. Synonyms: Monoclonal Cyclin Dependent Kinase 4 antibody, Anti Cyclin Dependent Kinase 4 antibody, CDK4 antibody, PSK-J3 antibody, CMM3 antibody, Cell division kinase 4 antibody.

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size