Leptin antibody
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- Target See all Leptin (LEP) Antibodies
- Leptin (LEP)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Leptin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
- Immunogen
- Leptin antibody was raised in mouse using highly pure recombinant human leptin as the immunogen.
- Clone
- M912276
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product LEP Primary Antibody
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- Application Notes
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ELISA: 2-4 µg/mL, WB: 0.2-0.4 µg/mL
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized from PBS.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Target
- Leptin (LEP)
- Alternative Name
- Leptin (LEP Products)
- Synonyms
- ob antibody, obese antibody, LEPD antibody, OB antibody, OBS antibody, leptin antibody, Lep antibody, LEP antibody, lep antibody
- Background
- Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Synonyms: Monoclonal Leptin antibody, Anti-Leptin antibody, Obesity antibody, OB antibody.
- Molecular Weight
- 16.2 kDa (predicted detection band MW)
- Pathways
- JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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