HIV1 Rev HxB2/HxB3 antibody (FITC)

Catalog No. ABIN934007

Product Details

Target: HIV1 Rev HxB2/HxB3

Reactivity: Human Immunodeficiency Virus (HIV)

Host: Mouse

Clonality: Monoclonal

Conjugate: FITC

Application: ELISA, Western Blotting (WB)

Purification: purified

Immunogen: HIV1, HxB2, HxB3 Rev antibody was raised in mouse using purified, full length rev (HIV-1 HxB2, HxB3) produced in E.coli Expression system as the immunogen.

Clone: 9G2G4D6E8

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:500-1:1000, WB: 1:500-1:1000
Optimal conditions should be determined by the investigator.

Comment:

Binds to recombinant rev (HIV-1 HxB2, HxB3) in ELISA and Western Blot. The antibody is epitope mapped to rev (70-84)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied liquid as a purified IgG in PBS buffer, with no preservatives added.

Preservative: Without preservative

Precaution of Use: Not tested for sterility or endotoxin content.

Handling Advice: Avoid repeated freeze/thaw cycles.
Product is photosensitive and should be protected from light.
Dilute only prior to immediate use.

Storage: 4 °C/-80 °C

Storage Comment: Store lyophilized product at 2-8 °C short term, following reconstitution, aliquot and store at -70 °C or lower.

Target Details

Target: HIV1 Rev HxB2/HxB3

Target Type: Viral Protein

Background: Rev is a HIV gene. The name rev stands for Regulator of Virion. The gene's protein product allows fragments of HIV mRNA that contain a Rev Response Element (RRE) to be exported from the nucleus to the cytoplasm. In the absence of the rev gene, the host RNA splicing machinery in the nucleus quickly splices the RNA so that only the smaller, regulatory proteins can be produced, in the presence of rev, RNA is exported from the nucleus before it can be spliced, so that the structural proteins and RNA genome can be produced. Synonyms: Monoclonal REV (HIV-1 HxB2, HxB3) antibody, Anti-REV (HIV-1 HxB2, HxB3) antibody.