CDH6 antibody (Extracellular Domain)

Catalog No. ABIN934345

Product Details anti-CDH6 Antibody

Target: CDH6 (K-Cadherin (CDH6))

Binding Specificity: Extracellular Domain

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDH6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Cadherin 6 antibody was raised in mouse using GST fusion protein of part of the extracellular domain of cadherin 6 (K-Cadherin) as the immunogen.

Clone: 2B6

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for CDH6

Target: CDH6 (K-Cadherin (CDH6))

Alternative Name: Cadherin 6 (CDH6 Products)

Synonyms: KCAD antibody, K-cadherin antibody, cad6 antibody, cadherin-6 antibody, CAD6 antibody, c-cad6B antibody, cadherin 6 antibody, Cdh6 antibody, CDH6 antibody

Background: Cadherin 6 protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. Synonyms: Monoclonal Cadherin 6 antibody, Anti Cadherin 6 antibody, K-Cadherin antibody, Kidney Cadherin antibody, KCAD antibody, Cadherin 6, type 2, K-cadherin (fetal kidney) antibody.

Pathways: Cell-Cell Junction Organization