alpha Fetoprotein antibody
-
- Target See all alpha Fetoprotein (AFP) Antibodies
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This alpha Fetoprotein antibody is un-conjugated
-
Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
-
Recognizes Alpha-fetoprotein (AFP).
Cellular Localization: Cytoplasmic. - Purification
- Purified
- Immunogen
- Human Alpha-Fetoprotein purified from Human cord serum
- Top Product
- Discover our top product AFP Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
-
- Target
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
- Abstract
- AFP Products
- Synonyms
- FETA antibody, HPAFP antibody, alpha fetoprotein antibody, alpha-fetoprotein antibody, AFP antibody, Afp antibody
- Background
- This is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasm, especially yolk sac tumors.Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
- Gene ID
- 20371
- NCBI Accession
- NP_001186276
- UniProt
- P02771
- Pathways
- C21-Steroid Hormone Metabolic Process
-