ADP Ribosylation Factor Like GTPase 1 (ARL1) (AA 80-108), (Middle Region) antibody

Details for Product No. ABIN950499, Supplier: Log in to see
Antigen
  • ARFL1
  • 2310008D22Rik
  • AU019749
  • zgc:92883
  • 72CDd
  • ARL1
  • ARL1_DROME
  • Arf
  • Arf72A
  • BcDNA:GM20805
  • CG 6025
  • CG6025
  • Dmel\CG6025
  • P25160
  • arf72A
  • arf[72A]
  • arl
  • arl1
  • dARL1p
  • dArl1
  • l(3)72Ae
  • l(3)72CDd
  • arfl1
  • ADP ribosylation factor like GTPase 1
  • ADP-ribosylation factor like GTPase 1
  • ADP-ribosylation factor-like 1
  • ADP-ribosylation factor-like protein 1
  • ADP ribosylation factor-like 1
  • ADP ribosylation factor like GTPase 1 L homeolog
  • ARL1
  • Arl1
  • arl-1
  • arl1
  • arl1.L
Epitope
AA 80-108, Middle Region
11
10
9
9
7
7
6
6
6
1
1
1
1
Reactivity
Human
84
26
24
4
4
4
4
4
4
3
3
2
1
1
1
Host
Rabbit
83
1
Clonality
Polyclonal
Conjugate
Un-conjugated
7
7
6
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
59
43
26
13
7
5
5
4
3
2
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide between 80-108 amino acids from the Central region of human ARL1
Isotype Ig Fraction
Specificity This antibody reacts to ARL1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Antigen
Alternative Name ARL1 (ARL1 Antibody Abstract)
Background The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.Synonyms: ADP-ribosylation factor-like protein 1
Gene ID 400
NCBI Accession NP_001168
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-ADP Ribosylation Factor Like GTPase 1 (ARL1) (AA 80-108), (Middle Region) antibody (ABIN950499) ARL1 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35µg/lane)...
Background publications Houghton, Chew, Lodeho, Goud, Gleeson: "The localization of the Golgin GCC185 is independent of Rab6A/A' and Arl1." in: Cell, Vol. 138, Issue 4, pp. 787-94, 2009 (PubMed).

Nishimoto-Morita, Shin, Mitsuhashi, Kitamura, Zhang, Johannes, Nakayama: "Differential effects of depletion of ARL1 and ARFRP1 on membrane trafficking between the trans-Golgi network and endosomes." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10583-92, 2009 (PubMed).

Lu, Tai, Hong: "Autoantigen Golgin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the trans-golgi network." in: Molecular biology of the cell, Vol. 15, Issue 10, pp. 4426-43, 2004 (PubMed).

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