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TNFRSF1A antibody (N-Term)
TNFRSF1A
Reactivity: Human
WB, FACS, IHC (p), IF, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNFRSF1A Antibody
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Target
See all TNFRSF1A Antibodies
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Binding Specificity
All epitopes for TNFRSF1A antibodies
AA 24-52, N-Term
Reactivity
All reactivities for TNFRSF1A antibodies
Human
Host
All hosts for TNFRSF1A antibodies
Rabbit
Clonality
All clonalities for TNFRSF1A antibodies
Polyclonal
Conjugate
All conjugates for TNFRSF1A antibodies
This TNFRSF1A antibody is un-conjugated
Application
All applications for TNFRSF1A antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
Specificity
This antibody detects CD120a / TNFR1 (N-term).
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Protein A column followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human TNFRSF1A
Isotype
Ig Fraction
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Discover our top product TNFRSF1A Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Target Details for TNFRSF1A
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Target
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Alternative Name
CD120a / TNFR1 (TNFRSF1A Products )
Synonyms
CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
Gene ID
7132
NCBI Accession
NP_001056
Pathways
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , Hepatitis C , Ubiquitin Proteasome Pathway
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