CD81 antibody

Catalog No. ABIN951414

Product Details anti-CD81 Antibody

Target: CD81

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD81 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This Polyclonal antibody is directed against Human CD81 protein.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD81

Target: CD81

Alternative Name: CD81 / TAPA1 (CD81 Products)

Synonyms: Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody

Background: TAPA1, or CD81, is a member of the transmembrane 4 superfamily, also known as the Tetraspanin family. Most of these members are cell surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TAPA1 is a cell surface glycoprotein that is known to complex with integrins. It appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. TAPA1 gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

Gene ID: 975

NCBI Accession: NP_004347

Pathways: Inositol Metabolic Process, Hepatitis C