Complex IV Subunit VIb (AA 58-86), (C-Term) antibody
Reactivity: Human
EIA, IHC (p), WB
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- Complex IV Subunit VIb
- Binding Specificity
- AA 58-86, C-Term
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Specificity
- This antibody reacts to COX6B1.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 58-86 amino acids from the C-terminal region of human COX6B1
- Isotype
- Ig Fraction
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- Complex IV Subunit VIb
- Background
- Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.Synonyms: COX6B, COX6B1, Cytochrome c oxidase subunit 6B1, Mitochondria Complex IV
- Molecular Weight
- 10192 Da
- Gene ID
- 1340
- NCBI Accession
- NP_001854
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