Cyclin C antibody (N-Term)

Catalog No. ABIN951753

The Rabbit Polyclonal anti-Cyclin C antibody (ABIN951753) specifically detects Cyclin C in WB, FACS and EIA. The antibody is reactive with Human samples.

Quick Overview for Cyclin C antibody (N-Term) (ABIN951753)

Target: Cyclin C (CCNC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin C antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-Cyclin C Antibody

Binding Specificity: AA 1-30, N-Term

Specificity: This antibody reacts to CCNC.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCNC

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Cyclin C

Target: Cyclin C (CCNC)

Alternative Name: Cyclin C

Background: The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: CCNC, Cyclin-C, SRB11 homolog, hSRB11

Molecular Weight: 33243 Da

Gene ID: 892

NCBI Accession: NP_005181

Pathways: Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha