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GAD antibody (C-Term)
GAD1
Reactivity: Human, Mouse, Rat
WB, IHC (p), IF
Host: Chicken
Polyclonal
unconjugated
Product Details anti-GAD Antibody
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Target
See all GAD (GAD1) Antibodies
GAD (GAD1)
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
Binding Specificity
All epitopes for GAD antibodies
C-Term
Reactivity
All reactivities for GAD antibodies
Human, Mouse, Rat
Host
All hosts for GAD antibodies
Chicken
Clonality
All clonalities for GAD antibodies
Polyclonal
Conjugate
All conjugates for GAD antibodies
This GAD antibody is un-conjugated
Application
All applications for GAD antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Specificity
Recognizes Glutamic Acid Decarboxylase (GAD1/GAD67).
Purification
Affinity Chromatography using a peptide column.
Immunogen
Synthetic peptide KLH conjugated corresponding to a region near the C-terminus of this gene product, and was 100% conserved between the Human (Q99259), Mouse (P48318) and Rat (NP_058703) gene products. After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks.
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL (based on Bradford assay readings using BSA as a standard)
Buffer
10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store the antibody undiluted in the dark at 2-8 °C.
Target Details for GAD
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Target
GAD (GAD1)
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
Alternative Name
GAD1 / GAD67 (GAD1 Products )
Synonyms
CPSQ1 antibody, GAD antibody, SCP antibody, GAD-67 antibody, cpsq1 antibody, gad1 antibody, gad1-A antibody, gad67 antibody, GAD67 antibody, GAD1 antibody, GLUTAMATE DECARBOXYLASE antibody, GLUTAMATE DECARBOXYLASE 1 antibody, MKP11.30 antibody, MKP11_30 antibody, glutamate decarboxylase antibody, EP10 antibody, GAD25 antibody, GAD44 antibody, Gad-1 antibody, Gad67 antibody, glutamate decarboxylase 1 antibody, glutamate decarboxylase 1 L homeolog antibody, glutamate decarboxylase antibody, glutamate decarboxylase 1b antibody, GAD1 antibody, gad1.1.L antibody, GAD antibody, Gad1 antibody, gad1b antibody
Background
Human Glutamic Acid Decarboxylase (GAD-67), [EC 4.1.1.15] is a 66,987 dalton protein (594 amino acids) selectively expressed in a subpopulation of GABAergic neurons of the CNS. It catalyzes the decarboxylation of glutamic acid, forming the inhibitory neurotransmitter β-amino butyric acid (GABA). It is also know as GAD-1.Synonyms: 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 1, Glutamate decarboxylase 67 kDa isoform
Gene ID
2571
NCBI Accession
NP_000808
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