GFAP
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Monoclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
2.0 mg/mL
Buffer
10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store the antibody undiluted in the dark at 2-8 °C.
Venables, Lapasset, Gadea, Fort, Klinck, Irimia, Vignal, Thibault, Prinos, Chabot, Abou Elela, Roux, Lemaitre, Tazi: "MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation." in: Nature communications, Vol. 4, pp. 2480, (2014) (PubMed).
Schoppmann, Ricken, Ilhan-Mutlu, Nirtl, Streubel, Preusser, Birner: "Downregulation of CIC does not associate with overexpression of ETV1 or MAP kinase pathway activation in gastrointestinal stromal tumors." in: Cancer investigation, Vol. 32, Issue 7, pp. 363-7, (2014) (PubMed).
Fofana, Xiao, Thumann, Turek, Zona, Tawar, Grunert, Thompson, Zeisel, Baumert: "A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
Heid, Rickelt, Zimbelmann, Winter, Schumacher, Dörflinger: "Lipid droplets, perilipins and cytokeratins--unravelled liaisons in epithelium-derived cells." in: PLoS ONE, Vol. 8, Issue 5, pp. e63061, (2013) (PubMed).
Kanemaru, Saitoh: "High-yield expression of mouse Aos1-Uba2-fusion SUMO-activating enzyme, mAU, in a baculovirus-insect cell system." in: Bioscience, biotechnology, and biochemistry, Vol. 77, Issue 7, pp. 1575-8, (2013) (PubMed).
Su, Chao, Huang, Weng, Jeng, Lai: "Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy." in: Journal of virology, Vol. 85, Issue 20, pp. 10561-71, (2011) (PubMed).
Huang, Zhou, Saberwal, Konieczna, Horvath, Katsoulidis, Platanias, Eklund: "Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription." in: Molecular and cellular biology, Vol. 30, Issue 19, pp. 4575-94, (2010) (PubMed).
Human GFAP is a 49,749 dalton protein (432 amino acids) expressed by astrocytes of the central nervous system. GFAP is an intermediate filament protein and acts as an intra-cellular structural component of the astrocytic cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Rare mutations of the GFAP gene in humans result in Alexander's disease, one of the leukodystrophies.Synonyms: Glial Fibrillary Acidic Protein